NEUROSCIENCE 2018 Activity – Scientific Abstract Intravascular blood flow displays temporal synchrony when basal ganglia neurotransmitter release is videotracked online in the normal state, while vasculature and cerebral release reflect temporal asynchrony during online videotracking of stroke: Sensing with Dual Laser Dopler Flowmetry and BRODERICK PROBE® Author Block: P.Broderick, R.Chowdhury, T. Alabed, S. Alamin, L.Wenning, CUNY Sch. of Med., New…
Neuromolecular imaging, a nanobiotechnology for Parkinson‘s disease: advancing pharmacotherapy for personalized medicine. Abstract Evaluating each patient and animal as its own control achieve personalized medicine, which honors the Hippocratic philosophy, explaining that “it is far more important to know what person has the disease than what disease the person has.” Similarly, individualizing molecular signaling directly…
Title: Selective detection of ascorbate, dopamine and serotonin with new N-Stearoylcerebroside and Laurate sensors: studies of oxidative stress in a morphine/ascorbate animal model. Keywords: Ascorbate; BRODERICK PROBE® sensors; dehydroascorbic acid; dopamine; drug addiction; electrodes; Laurate sensor; microelectrodes; microvoltammetry; morphine; naloxone; neuromolecular imaging (NMI); N-Stearoylcerebroside sensor; nucleus accumbens; sensors; serotonin; opioids; oxidative stress; pain; stroke. Corresponding Author: Medical Professor Patricia Ann Broderick, Ph.D. Corresponding Author’s…
ABSTRACT Females are significantly more likely to become addicted to nicotine, among other drugs. Intensive research has been conducted on nicotinic acetylcholine receptors as the agents responsible for nicotine addiction. However, the mechanism by which females become more susceptible to addiction and its effects are not known. In an effort to address the sex differences…
Caffeine is HOT – People Want to Know About It. By Dr. Patricia A. Broderick Dr. Broderick is medical professor of Physiology, Pharmacology and Neuroscience at the Sophie Davis School of Biomedical Education and director of the Pharmacology course at the School’s Physician Assistant Program, in conjunction with Harlem Hospital. Dr. Broderick holds an…
Biosensors for Brain Trauma and Dual Laser Doppler Flowmetry: Enoxaparin Simultaneously Reduces Stroke-Induced Dopamine and Blood Flow while Enhancing Serotonin and Blood Flow in Motor Neurons of Brain, In Vivo Patricia A. Broderick 1,2,3,* and Edwin H. Kolodny 3 1 Department of Physiology & Pharmacology, Sophie Davis School of Biomedical Education, CCNY, New York, NY 10031, USA…
Background: Sex differences in cocaine abuse are well established. Females have a higher sensitivity and thus higher vulnerability to cocaine abuse compared to males. There are many studies showing that sensitivity to cocaine reward varies during the estrus cycle. Methods: Vaginal smears were examined through a DIFF staining kit and viewed through a microscope to determine…
